Joining forces to develop individualized antisense oligonucleotides for patients with brain or eye diseases: the example of the Dutch Center for RNA Therapeutics

Annemieke Aartsma-Rus, Rob W.J. Collin, Ype Elgersma, Marlen C. Lauffer, Willeke van Roon-Mom, 2024 (sagepub.com)

ExonViz: A website and Python package to visualize transcripts and genetic variants

Redmar R. van den Berg, Marlen C. Lauffer, Jeroen F.J. Laros

medRxiv 2024.09.18.24313945; doi: https://doi.org/10.1101/2024.09.18.24313945

The first paper is a joint effort by DCRT partners LUMC, Radboudumc and ErasmusMC and describes the work that the DCRT has been doing towards the development of an individualized ASO treatment for patients with an ultra-rare genetic, progressive disorder of the brain or the eye. The second paper describes the tool that Team LUMC has developed to visualize genetic transcripts and variants. Feel free to try out the ExonViz tool on our website: Exonviz (rnatherapy.nl).

posted on September 26, 2024