No less than three DCRT coordinators actively contributed to the workshop of the Delivery of Antisense RNA Therapy (DARTER) COST Action that took place from July 19-21. DARTER is a network that aims to foster and facilitate antisense oligonucleotide research in Europe by achieving consensus on which model systems to use to improve delivery and study safety and toxicity of oligonucleotide therapies. COST Actions are funded by the cooperation of science and technology (COST. These networks are open to new participants also after the network has initiated. For more information on DARTER look on the antisenserna website.
During the workshop Willeke van Roon-Mom presented on delivery to brain and cell and animal model systems to test this. Rob Collin presented on delivery to the eye and the development of antisense oligonucleotide therapies for genetic retinal diseases. Finally, Annemieke Aartsma-Rus presented in the “negative results” session. DARTER and DCRT strongly believe that it is important to publish also about hypotheses and ideas that turned out not to work. Sharing these findings will avoid unnecessary duplication of work. Furthermore, hypotheses that are disproven also advance science.